# OnCo record idea-microbiome-io-fmt (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-microbiome-io-fmt/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-microbiome-io-fmt" ;
  schema:name "Microbiome transplant as a routine immunotherapy adjunct"@en ;
  schema:description "Stool transplants from immunotherapy responders have rescued some non-responders in melanoma. If defined bacterial cocktails work as well, every immunotherapy patient could get one."@en ;
  schema:url <https://onco.cc/ideas/idea-microbiome-io-fmt/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.abf3363>, <https://doi.org/10.1126/science.abb5920> ;
  onco:tag "mechanism", "open-question" ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:institutions <https://onco.cc/institutions/md-anderson/>, <https://onco.cc/institutions/gustave-roussy/> ;
  onco:pathways <https://onco.cc/pathways/microbiome-tumour/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/polymorphic-microbiomes/> ;
  onco:trials <https://onco.cc/trials/checkmate-227/>, <https://onco.cc/trials/checkmate-915/>, <https://onco.cc/trials/fianlimab-phase3-melanoma/>, <https://onco.cc/trials/keynote-042/>, <https://onco.cc/trials/relativity-098/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-davar-science/>, <https://onco.cc/key-papers/paper-baruch-science/>, <https://onco.cc/key-papers/paper-topalian-anti-pd1-nejm-2012/>, <https://onco.cc/key-papers/paper-pd-1-nsclc-am-j-clin-oncol-2016/>, <https://onco.cc/key-papers/paper-kras-nsclc-cancer-discov-2018/> .