# OnCo record idea-moon-automated-combination-discovery (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-moon-automated-combination-discovery/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-moon-automated-combination-discovery" ;
  schema:name "Automated combination discovery: patient-sample screens feeding Bayesian platform trials"@en ;
  schema:description "There are far more possible drug combinations than can ever be tried in patients. Test thousands on living samples of real tumours, then feed only the winners into adaptive trials."@en ;
  schema:url <https://onco.cc/ideas/idea-moon-automated-combination-discovery/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.cell.2017.11.009> ;
  onco:related <https://onco.cc/ideas/idea-organoid-guided-adc/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/functional-drug-testing/>, <https://onco.cc/technologies/organoids/>, <https://onco.cc/technologies/ai-drug-design/> ;
  onco:terms <https://onco.cc/terms/basket-umbrella-platform/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-combination-space/>, <https://onco.cc/bottlenecks/b-preclinical-models/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-palmer-cell/> .