# OnCo record idea-pdac-enzyme-replacement-prescribing-by-default (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-pdac-enzyme-replacement-prescribing-by-default/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-pdac-enzyme-replacement-prescribing-by-default" ;
  schema:name "Pancreatic enzyme replacement by default: prescribe at diagnosis, audit the rate, and run the trial that settles survival"@en ;
  schema:description "The pancreas makes the enzymes that digest food, and a cancer in it, or the operation to remove it, leaves most patients unable to absorb what they eat. Capsules replacing those enzymes are cheap and recommended, yet UK records show only one patient in five was prescribed them. The proposal is to prescribe by default at diagnosis, publish each hospital's rate, and run the trial never done."@en ;
  schema:url <https://onco.cc/ideas/idea-pdac-enzyme-replacement-prescribing-by-default/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://europepmc.org/article/MED/30385188>, <https://www.nice.org.uk/guidance/ng85>, <https://www.natcan.org.uk/reports/?audit=pancreatic> ;
  onco:tag "pancreatic-evidence" ;
  onco:related <https://onco.cc/ideas/idea-pdac-cachexia-trials-embedded-in-chemotherapy-trials/>, <https://onco.cc/ideas/idea-pdac-uk-active-treatment-rate-audit-and-target/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:sections <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/nutrition-lifestyle/> ;
  onco:terms <https://onco.cc/terms/whipple/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-cachexia-supportive/>, <https://onco.cc/bottlenecks/b-knowledge-diffusion/>, <https://onco.cc/bottlenecks/b-care-fragmentation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-roberts-pert-survival-pancreatic-cancer-pancreatology-2019/>, <https://onco.cc/key-papers/paper-traverso-longmire-pylorus-preservation-pancreaticoduodenectomy-sgo-1978/> .