# OnCo record idea-prev-brca1-denosumab-prevention (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-prev-brca1-denosumab-prevention/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-prev-brca1-denosumab-prevention" ;
  schema:name "A bone drug to prevent breast cancer in BRCA1 carriers"@en ;
  schema:description "BRCA1 breast cancers seem to grow from cells driven by the RANK signal. Denosumab blocks it and is already used for bone. A trial is testing whether it prevents these cancers."@en ;
  schema:url <https://onco.cc/ideas/idea-prev-brca1-denosumab-prevention/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2017.73.6314> ;
  onco:cancers <https://onco.cc/cancers/tnbc/> ;
  onco:sections <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/technologies/chemoprevention/> ;
  onco:targets <https://onco.cc/targets/brca/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-hereditary-risk/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-childers-j-clin-oncol/> .