# OnCo record idea-prev-glp1-cancer-prevention-rct (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-prev-glp1-cancer-prevention-rct/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-prev-glp1-cancer-prevention-rct" ;
  schema:name "A trial of GLP-1 weight-loss drugs with cancer as the primary outcome"@en ;
  schema:description "Obesity raises the risk of 13 cancers, and GLP-1 weight-loss drugs are already in routine use for diabetes and obesity. Observational data hint that they cut obesity-related cancers but confounding is severe, so a randomised trial in adults aged 50 to 70 with a BMI of 30 or more should make cancer the primary outcome."@en ;
  schema:url <https://onco.cc/ideas/idea-prev-glp1-cancer-prevention-rct/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.3322/caac.21440> ;
  onco:cancers <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/hcc/> ;
  onco:sections <https://onco.cc/fronts/prevention/> ;
  onco:technologies <https://onco.cc/technologies/chemoprevention/> ;
  onco:companies <https://onco.cc/companies/eli-lilly/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-prevention-adoption/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-islami-ca-cancer-j-clin/> .