# OnCo record idea-prev-lynch-frameshift-vaccine-rct (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-prev-lynch-frameshift-vaccine-rct/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-prev-lynch-frameshift-vaccine-rct" ;
  schema:name "A randomised trial of a shared-antigen vaccine to prevent Lynch syndrome cancers"@en ;
  schema:description "Lynch syndrome tumours share predictable mutations the immune system can target. A vaccine in early trials could be tested to see if it prevents polyps and cancers in carriers."@en ;
  schema:url <https://onco.cc/ideas/idea-prev-lynch-frameshift-vaccine-rct/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2017.73.6314> ;
  onco:related <https://onco.cc/ideas/idea-interception-vaccines/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/endometrial/> ;
  onco:sections <https://onco.cc/fronts/prevention/>, <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/shared-antigen-vaccine/> ;
  onco:companies <https://onco.cc/companies/nouscom/> ;
  onco:terms <https://onco.cc/terms/msi/>, <https://onco.cc/terms/neoantigen/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-hereditary-risk/>, <https://onco.cc/bottlenecks/b-prevention-adoption/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-childers-j-clin-oncol/> .