# OnCo record idea-prostate-bipolar-androgen-therapy-phase-3-on-pfs2 (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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a schema:CreativeWork ;
onco:kind "idea" ;
schema:identifier "idea-prostate-bipolar-androgen-therapy-phase-3-on-pfs2" ;
schema:name "Take high-dose testosterone to phase 3, with progression-free survival through the second line as the primary endpoint"@en ;
schema:alternateName "bipolar androgen therapy phase 3"@en, "supraphysiological testosterone prostate phase 3"@en, "BAT resensitisation trial"@en ;
schema:description "Giving men with castration-resistant prostate cancer large doses of the hormone the treatment has spent years removing makes a third of them respond, and makes half of them respond again to the drug that had stopped working. It has never been taken to a definitive trial, partly because the endpoint that shows the benefit is not the one trials usually use."@en ;
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schema:dateModified "2026-09-25"^^xsd:date ;
onco:tag "prostate-evidence" ;
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