# OnCo record idea-ras-inhibitor-neoadjuvant-pdac (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-ras-inhibitor-neoadjuvant-pdac/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-ras-inhibitor-neoadjuvant-pdac" ;
  schema:name "RAS(ON) inhibitors to convert unresectable pancreatic cancer to resectable"@en ;
  schema:description "If daraxonrasib shrinks metastatic tumours this well, use it before surgery to make more locally advanced tumours operable."@en ;
  schema:url <https://onco.cc/ideas/idea-ras-inhibitor-neoadjuvant-pdac/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06625320> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/kras-inhibitors/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:targets <https://onco.cc/targets/kras/> ;
  onco:drugs <https://onco.cc/drugs/daraxonrasib/>, <https://onco.cc/drugs/zoldonrasib/>, <https://onco.cc/drugs/folfirinox/> ;
  onco:trials <https://onco.cc/trials/rasolute-302/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-nct05379985-n-engl-j-med-2026/>, <https://onco.cc/key-papers/paper-daraxonrasib-pancreatic-n-engl-j-med-2026/>, <https://onco.cc/key-papers/paper-daraxonrasib-pancreatic-cureus-2026/> .