# OnCo record idea-reg-aspirin-pik3ca-implementation (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-reg-aspirin-pik3ca-implementation/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-reg-aspirin-pik3ca-implementation" ;
  schema:name "Get biomarker-directed aspirin after colorectal surgery into labels and guidelines"@en ;
  schema:description "A Swedish trial found that cheap aspirin roughly halved recurrence in colorectal cancer patients with a particular tumour mutation. Nobody is going to market it, so health systems must adopt it deliberately."@en ;
  schema:url <https://onco.cc/ideas/idea-reg-aspirin-pik3ca-implementation/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://www.nejm.org/doi/full/10.1056/NEJMoa2504650> ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:targets <https://onco.cc/targets/pik3ca/> ;
  onco:institutions <https://onco.cc/institutions/karolinska/>, <https://onco.cc/institutions/esmo/> ;
  onco:pathways <https://onco.cc/pathways/pi3k-akt-mtor/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-generic-repurposing/>, <https://onco.cc/bottlenecks/b-knowledge-diffusion/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pik3ca-colorectal-lancet-oncol-2011/>, <https://onco.cc/key-papers/paper-pik3ca-colorectal-acta-oncol-2014/>, <https://onco.cc/key-papers/paper-pik3ca-colorectal-j-clin-oncol-2013/> .