# OnCo record idea-senolytics-after-chemo (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-senolytics-after-chemo/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-senolytics-after-chemo" ;
  schema:name "One-two punch: clear senescent cells after chemotherapy"@en ;
  schema:description "Chemotherapy leaves behind senescent cells that inflame tissues and help tumours relapse. A short course of senolytic drugs afterwards might reduce relapse and long-term side effects at once."@en ;
  schema:url <https://onco.cc/ideas/idea-senolytics-after-chemo/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1158/2159-8290.CD-16-0241> ;
  onco:tag "mechanism", "open-question" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/ovarian/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/> ;
  onco:technologies <https://onco.cc/technologies/protac-degrader/>, <https://onco.cc/technologies/geriatric-assessment/> ;
  onco:targets <https://onco.cc/targets/bcl2/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/mayo-clinic/> ;
  onco:pathways <https://onco.cc/pathways/senescence/>, <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:terms <https://onco.cc/terms/senescent-cells/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-demaria-cancer-discov/> .