# OnCo record idea-tcr-t-beyond-hla-a2 (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tcr-t-beyond-hla-a2/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tcr-t-beyond-hla-a2" ;
  schema:name "Extending sarcoma TCR-T beyond HLA-A*02"@en ;
  schema:description "Today's engineered T-cell therapies for sarcoma only work in the ~40-50% of people with one particular HLA type; new receptors for other HLA types would open them to everyone."@en ;
  schema:url <https://onco.cc/ideas/idea-tcr-t-beyond-hla-a2/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03967223> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/> ;
  onco:technologies <https://onco.cc/technologies/tcr-t/> ;
  onco:targets <https://onco.cc/targets/mage-a4/> ;
  onco:drugs <https://onco.cc/drugs/afamitresgene-autoleucel/>, <https://onco.cc/drugs/letetresgene-autoleucel/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-spearhead-1-lancet-2024/> .