# OnCo record idea-tr1-ctdna-guided-stop-in-metastatic-disease (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-ctdna-guided-stop-in-metastatic-disease/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-ctdna-guided-stop-in-metastatic-disease" ;
  schema:name "Use tumour DNA in blood to decide when to pause treatment in metastatic cancer"@en ;
  schema:description "If a blood test shows no tumour DNA after months of treatment, a trial could test pausing the drug and restarting only when the DNA reappears, giving patients time off without waiting for scans to show growth."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-ctdna-guided-stop-in-metastatic-disease/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1136/bmj.j4530> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:companies <https://onco.cc/companies/natera/>, <https://onco.cc/companies/guardant-health/> ;
  onco:terms <https://onco.cc/terms/ctdna/> ;
  onco:trials <https://onco.cc/trials/dynamic/>, <https://onco.cc/trials/imvigor011/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-davis-bmj/> .