# OnCo record idea-tr1-geriatric-dose-finding-cohorts (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-geriatric-dose-finding-cohorts/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-geriatric-dose-finding-cohorts" ;
  schema:name "Dose-finding in older and frail patients, not extrapolation from fit ones"@en ;
  schema:description "The dose for a frail 80-year-old is guessed from what fit 55-year-olds tolerated. Running dose-finding in older patients directly, using frailty assessment, would give doses they can actually take."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-geriatric-dose-finding-cohorts/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://www.fda.gov/about-fda/oncology-center-excellence/project-optimus> ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/aml/> ;
  onco:technologies <https://onco.cc/technologies/geriatric-assessment/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/>, <https://onco.cc/bottlenecks/b-aging-comorbidity/> .