# OnCo record idea-tr1-low-dose-immunotherapy-for-lmic (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-low-dose-immunotherapy-for-lmic/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-low-dose-immunotherapy-for-lmic" ;
  schema:name "Confirm ultra-low-dose immunotherapy so it can be afforded where most patients live"@en ;
  schema:description "A single-centre trial at Tata Memorial found that adding nivolumab at about a twentieth of the usual dose to chemotherapy improved outcomes in head and neck cancer. Confirmatory trials against standard-dose immunotherapy are needed before low-dose labels could make immunotherapy affordable for millions."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-low-dose-immunotherapy-for-lmic/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://www.fda.gov/about-fda/oncology-center-excellence/project-optimus> ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/cervical/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/> ;
  onco:institutions <https://onco.cc/institutions/tata-memorial/> ;
  onco:trials <https://onco.cc/trials/checkmate-227/>, <https://onco.cc/trials/harmoni-3/>, <https://onco.cc/trials/keynote-024-189/>, <https://onco.cc/trials/keynote-042/>, <https://onco.cc/trials/keynote-a18/> ;
  onco:people <https://onco.cc/people/patil-vijay/>, <https://onco.cc/people/prabhash-kumar/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/>, <https://onco.cc/bottlenecks/b-global-access/>, <https://onco.cc/bottlenecks/b-drug-pricing/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-checkmate-017-nejm-2015/> .