# OnCo record idea-tr1-pre-consented-cohort-randomisation (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-pre-consented-cohort-randomisation/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-pre-consented-cohort-randomisation" ;
  schema:name "Pre-consented cohorts that can be randomised to future trials (TwiCs)"@en ;
  schema:description "Patients join a long-term cohort once and agree in advance that they may be offered new treatments as they appear, while others in the cohort serve as the comparison group. No new trial has to start from zero."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-pre-consented-cohort-randomisation/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1093/jnci/djy221> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/colorectal/> ;
  onco:institutions <https://onco.cc/institutions/nki/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-enrolment/>, <https://onco.cc/bottlenecks/b-trial-design/> .