# OnCo record idea-tr1-seamless-2-3-with-prespecified-go (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-seamless-2-3-with-prespecified-go/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-seamless-2-3-with-prespecified-go" ;
  schema:name "Seamless phase 2/3 with pre-registered go rules as the default for new agents"@en ;
  schema:description "Instead of stopping after the mid-sized trial, waiting a year, then starting the big one, run them as one study with a clear pre-agreed rule for continuing. This saves a year or more per drug."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-seamless-2-3-with-prespecified-go/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1136/bmj.j4530> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-davis-bmj/> .