# OnCo record idea-tr1-surrogate-validation-programme (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr1-surrogate-validation-programme/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr1-surrogate-validation-programme" ;
  schema:name "An independent programme that validates surrogate endpoints, setting by setting"@en ;
  schema:description "Trials often measure a stand-in for survival, such as time until the cancer grows on scans. An independent body would test, for each cancer and treatment type, whether the stand-in actually predicts survival, and publish the answer."@en ;
  schema:url <https://onco.cc/ideas/idea-tr1-surrogate-validation-programme/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://www.fda.gov/about-fda/oncology-center-excellence/project-endpoint> ;
  onco:institutions <https://onco.cc/institutions/esmo/>, <https://onco.cc/institutions/asco/> ;
  onco:terms <https://onco.cc/terms/pfs/>, <https://onco.cc/terms/os/>, <https://onco.cc/terms/pcr/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/orr/>, <https://onco.cc/terms/accelerated-approval/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-biomarker-validation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-reproducibility-project-cancer-biology-elife-2021/> .