# OnCo record idea-tr2-failure-taxonomy (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-tr2-failure-taxonomy/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-tr2-failure-taxonomy" ;
  schema:name "A machine-readable taxonomy of why cancer drugs fail"@en ;
  schema:description "Drugs fail for distinct reasons: wrong target, drug never reached it, unacceptable toxicity, unselected population or poor trial design. A shared machine-readable taxonomy applied to every discontinued oncology programme in public pipeline databases would show where the system breaks, as AstraZeneca and Pfizer's own attrition analyses did."@en ;
  schema:url <https://onco.cc/ideas/idea-tr2-failure-taxonomy/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMsa1409364> ;
  onco:related <https://onco.cc/ideas/idea-tr2-termination-reports/>, <https://onco.cc/ideas/idea-tr2-target-failure-index/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-negative-results/>, <https://onco.cc/bottlenecks/b-translational-valley/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-anderson-n-engl-j-med/> .