# OnCo record idea-upgrade-carboplatin-gfr-estimate-outcome-study (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/ideas/idea-upgrade-carboplatin-gfr-estimate-outcome-study/>
  a schema:CreativeWork ;
  onco:kind "idea" ;
  schema:identifier "idea-upgrade-carboplatin-gfr-estimate-outcome-study" ;
  schema:name "Compare carboplatin dosed by BSA-adjusted CKD-EPI eGFR with Cockcroft-Gault on toxicity and response"@en ;
  schema:description "Carboplatin doses depend on an estimate of kidney function. The 2025 international guideline (ADDIKD) recommends a newer estimate (BSA-adjusted CKD-EPI) over the old Cockcroft-Gault formula when kidney function cannot be measured directly, because it is more accurate. No study has yet shown that switching changes side effects or how well treatment works."@en ;
  schema:url <https://onco.cc/ideas/idea-upgrade-carboplatin-gfr-estimate-outcome-study/> ;
  schema:dateModified "2026-11-11"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.eclinm.2025.103102>, <https://doi.org/10.1016/j.eclinm.2025.103161>, <https://doi.org/10.1200/JCO.2017.72.7578> ;
  onco:tag "protocol-upgrade", "upgrade:promising", "evidence:moderate" ;
  onco:sections <https://onco.cc/fronts/chemotherapy/> ;
  onco:technologies <https://onco.cc/technologies/carboplatin-calvert-dosing/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-dose-optimisation/> .