# OnCo record idea-upgrade-hand-foot-cooling-compression-during-taxanes (idea). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
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a schema:CreativeWork ;
onco:kind "idea" ;
schema:identifier "idea-upgrade-hand-foot-cooling-compression-during-taxanes" ;
schema:name "Frozen gloves or tight surgical gloves offered during every weekly taxane infusion"@en ;
schema:description "Cooling the hands and feet, or squeezing them in tight surgical gloves, during paclitaxel infusions narrows blood vessels while the drug level peaks. In one randomised trial, moderate or worse nerve damage in the treated hand fell from 50 to 29 per cent with cooling; a larger trial of frozen gloves and socks missed its main target but found less numbness."@en ;
schema:url ;
schema:dateModified "2026-10-20"^^xsd:date ;
schema:citation , , , ;
onco:tag "protocol-upgrade", "upgrade:promising", "evidence:moderate" ;
onco:related ;
onco:cancers ;
onco:sections , ;
onco:technologies ;
onco:drugs , ;
onco:terms ;
onco:bottlenecks ;
onco:keyPapers .