# OnCo record idh1-r132 (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/idh1-r132/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "idh1-r132" ;
  schema:name "IDH1 R132 mutation"@en ;
  schema:alternateName "IDH1 R132H"@en, "IDH1 R132C"@en, "IDH1 mutation"@en, "IDH1-mutant"@en, "IDH1 R132"@en, "mIDH1"@en, "susceptible IDH1 mutation"@en ;
  schema:description "IDH1 R132 mutations turn a metabolic enzyme into a producer of the oncometabolite 2-HG. They define lower-grade gliomas and occur in acute myeloid leukaemia and bile duct cancer, each with an approved IDH1 inhibitor."@en ;
  schema:url <https://onco.cc/biomarkers/idh1-r132/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=65d254c0-67ad-42c4-b972-ad463b755b2d>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=31405fee-55b7-4857-987e-2724ee76be84> ;
  onco:tag "biomarker", "idh" ;
  onco:related <https://onco.cc/biomarkers/idh2-mutation/>, <https://onco.cc/biomarkers/1p19q-codeletion-readout/>, <https://onco.cc/biomarkers/mgmt-promoter-methylation/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-idh/>, <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/idh-mutant-astrocytoma/>, <https://onco.cc/cancers/oligodendroglioma/>, <https://onco.cc/cancers/mds/> ;
  onco:drugs <https://onco.cc/drugs/ivosidenib/>, <https://onco.cc/drugs/olutasidenib/>, <https://onco.cc/drugs/vorasidenib/>, <https://onco.cc/drugs/oncomine-dx-target-test/> ;
  onco:terms <https://onco.cc/terms/ngs/> .