# OnCo record igf1r (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/igf1r/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "igf1r" ;
  schema:name "IGF-1 receptor (IGF1R)"@en ;
  schema:description "The IGF-1 receptor is a growth-factor receptor that many cancers use to survive; a decade of antibodies and kinase inhibitors against it failed in trials, a cautionary tale in oncology drug development."@en ;
  schema:url <https://onco.cc/targets/igf1r/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Insulin-like_growth_factor_1_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5465>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000140443>, <https://www.uniprot.org/uniprotkb/P08069/entry>, <https://www.ncbi.nlm.nih.gov/gene/3480> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P08069/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5465>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL1957> ;
  schema:alternateName "IGF1R" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1986"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/ewing-sarcoma/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/breast-hr-positive/> .