# OnCo record il10 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/il10/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "il10" ;
  schema:name "Interleukin-10 (IL10)"@en ;
  schema:alternateName "IL-10"@en, "interleukin 10"@en, "CSIF"@en, "IL10" ;
  schema:description "IL-10 is a calming signal that many immune cells release; tumours and the viruses behind them raise it to keep the immune system quiet. Oddly, the main cancer drug built on it gave more IL-10 rather than less, and failed."@en ;
  schema:url <https://onco.cc/targets/il10/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5962>, <https://www.uniprot.org/uniprotkb/P22301/entry>, <https://www.ncbi.nlm.nih.gov/gene/3586>, <https://europepmc.org/article/MED/25302175>, <https://clinicaltrials.gov/study/NCT03382899> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5962>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000136634>, <https://www.uniprot.org/uniprotkb/P22301/entry>, <https://www.ncbi.nlm.nih.gov/gene/3586> ;
  onco:related <https://onco.cc/targets/tgfb1/>, <https://onco.cc/terms/macrophage/> ;
  onco:drugs <https://onco.cc/drugs/lb4330/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/>, <https://onco.cc/pathways/tgf-beta/> .