# OnCo record il11ra (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/il11ra/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "il11ra" ;
  schema:name "IL-11 receptor alpha"@en ;
  schema:description "The IL-11 receptor was the target of oprelvekin, the first drug approved to prevent the severe platelet falls that chemotherapy causes; the drug was withdrawn in 2011 and thrombopoietin agonists took over the problem."@en ;
  schema:url <https://onco.cc/targets/il11ra/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Interleukin_11_receptor_alpha_subunit>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5967>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000137070>, <https://www.uniprot.org/uniprotkb/Q14626/entry>, <https://www.ncbi.nlm.nih.gov/gene/3590> ;
  schema:citation <https://www.uniprot.org/uniprotkb/Q14626/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5967>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL2050> ;
  onco:tag "chembl-gap" ;
  schema:alternateName "IL11RA" ;
  onco:targetClass "surface-antigen" ;
  onco:firstDescribed "1995"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/jak2/> ;
  onco:cancers <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/colorectal/> ;
  onco:drugs <https://onco.cc/drugs/oprelvekin/> ;
  onco:terms <https://onco.cc/terms/thrombocytopenia/> .