# OnCo record imbrave050 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/imbrave050/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "imbrave050", "NCT04102098" ;
  schema:name "IMbrave050"@en ;
  schema:description "The first adjuvant immunotherapy trial in liver cancer looked positive early, then the benefit vanished with longer follow-up."@en ;
  schema:url <https://onco.cc/trials/imbrave050/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04102098>, <https://www.journal-of-hepatology.eu/article/S0168-8278(26)00017-6/fulltext> ;
  onco:status "negative" ;
  onco:tag "failure", "lesson:interim-analysis" ;
  onco:phase "3" ;
  schema:startDate "2019-12-31" ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/hcc-early/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/atezolizumab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:people <https://onco.cc/people/ann-lii-cheng/> .