# OnCo record impassion130 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/impassion130/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "impassion130", "NCT02425891" ;
  schema:name "IMpassion130"@en ;
  schema:description "IMpassion130 was the first immunotherapy success in breast cancer, later undermined when a sister trial failed and the approval was withdrawn."@en ;
  schema:url <https://onco.cc/trials/impassion130/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02425891>, <https://doi.org/10.1056/NEJMoa1809615>, <https://doi.org/10.1016/j.annonc.2021.05.355>, <https://www.nice.org.uk/guidance/ta639> ;
  onco:status "mixed" ;
  onco:phase "3" ;
  schema:startDate "2015-06-23" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-metastatic/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/paclitaxel/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:trials <https://onco.cc/trials/impassion131/>, <https://onco.cc/trials/keynote-355/>, <https://onco.cc/trials/neotrip/> ;
  onco:people <https://onco.cc/people/rebecca-dent/>, <https://onco.cc/people/peter-schmid/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-rugo-pd-l1-assay-comparison-impassion130-jnci-2021/>, <https://onco.cc/key-papers/paper-impassion130-n-engl-j-med-2018/>, <https://onco.cc/key-papers/paper-impassion130-lancet-oncol-2020-update/> .