# OnCo record impassion131 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/impassion131/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "impassion131", "NCT03125902" ;
  schema:name "IMpassion131"@en ;
  schema:description "IMpassion131 was the sister trial to the first immunotherapy success in breast cancer. It failed, and the approval it was meant to confirm was withdrawn."@en ;
  schema:url <https://onco.cc/trials/impassion131/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03125902>, <https://www.annalsofoncology.org/article/S0923-7534(21)02073-7/fulltext>, <https://doi.org/10.1016/j.annonc.2021.05.801> ;
  onco:status "negative" ;
  onco:tag "failure", "lesson:partner-and-biomarker" ;
  onco:phase "3" ;
  schema:startDate "2017-08-25" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-metastatic/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/cps/>, <https://onco.cc/terms/accelerated-approval/> ;
  onco:trials <https://onco.cc/trials/impassion130/>, <https://onco.cc/trials/keynote-355/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-impassion131-ann-oncol-2021/> .