# OnCo record inflammation-nfkb (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/inflammation-nfkb/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "inflammation-nfkb" ;
  schema:name "Inflammation & NF-κB"@en ;
  schema:description "Chronic inflammation is soil for cancer: it feeds growth signals, DNA damage, and immune suppression. The NF-κB switch inside cells is the master relay, and colitis, hepatitis, and H. pylori gastritis are the clinical proof."@en ;
  schema:url <https://onco.cc/pathways/inflammation-nfkb/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/NF-κB> ;
  owl:sameAs <http://www.wikidata.org/entity/Q411114> ;
  schema:citation <https://doi.org/10.1016/j.immuni.2019.06.025> ;
  onco:tag "mechanism" ;
  onco:cancers <https://onco.cc/cancers/gallbladder/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/chemoprevention/>, <https://onco.cc/technologies/hpv-vaccine/> ;
  onco:targets <https://onco.cc/targets/btk/> ;
  onco:drugs <https://onco.cc/drugs/ibrutinib/>, <https://onco.cc/drugs/zanubrutinib/> ;
  onco:institutions <https://onco.cc/institutions/ucsf/>, <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/dkfz/> ;
  onco:pathways <https://onco.cc/pathways/jak-stat/>, <https://onco.cc/pathways/senescence/>, <https://onco.cc/pathways/tumor-microenvironment/>, <https://onco.cc/pathways/cachexia-biology/> ;
  onco:terms <https://onco.cc/terms/tumor-promoting-inflammation/>, <https://onco.cc/terms/crs/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-greten-immunity/> .