# OnCo record inherited-skin-cancer-syndromes (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/inherited-skin-cancer-syndromes/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "inherited-skin-cancer-syndromes" ;
  schema:name "Inherited syndromes that cause skin cancer: Gorlin syndrome and xeroderma pigmentosum"@en ;
  schema:alternateName "Gorlin syndrome"@en, "Gorlin-Goltz syndrome"@en, "naevoid basal cell carcinoma syndrome"@en, "nevoid basal cell carcinoma syndrome"@en, "NBCCS"@en, "BCNS"@en, "basal cell naevus syndrome"@en, "PTCH1"@en, "SUFU"@en, "xeroderma pigmentosum"@en, "XP"@en, "inherited skin cancer syndrome"@en, "genetic skin cancer syndrome"@en ;
  schema:description "Two rare inherited conditions cause skin cancer decades earlier and in far greater numbers than sun exposure alone. Gorlin syndrome causes many basal cell carcinomas from a young age through a fault in the same pathway the hedgehog inhibitor drugs block. Xeroderma pigmentosum leaves cells unable to repair ultraviolet damage at all."@en ;
  schema:url <https://onco.cc/terms/inherited-skin-cancer-syndromes/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Nevoid_basal_cell_carcinoma_syndrome> ;
  schema:citation <https://doi.org/10.1007/s10689-021-00247-z>, <https://doi.org/10.1002/ajmg.a.33139>, <https://doi.org/10.1136/jmg.30.6.460>, <https://doi.org/10.1186/1750-1172-6-70>, <https://publications.iarc.who.int/Book-And-Report-Series/Who-Classification-Of-Tumours/Skin-Tumours-2025>, <https://publications.iarc.who.int/Book-And-Report-Series/Who-Classification-Of-Tumours/WHO-Classification-Of-Skin-Tumours-2018> ;
  onco:related <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/pathways/field-cancerisation/>, <https://onco.cc/terms/hereditary-cancer-syndromes/> ;
  onco:cancers <https://onco.cc/cancers/basal-cell-carcinoma/>, <https://onco.cc/cancers/cutaneous-scc/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/locally-advanced-bcc/>, <https://onco.cc/cancers/bowens-disease/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/prevention/> ;
  onco:terms <https://onco.cc/terms/bcc-growth-pattern/>, <https://onco.cc/terms/keratinocyte-cancer/>, <https://onco.cc/terms/actinic-keratosis/>, <https://onco.cc/terms/skin-cancer-high-risk-features/> .