# OnCo record int-0116 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/int-0116/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "int-0116" ;
  schema:name "INT-0116 (Macdonald trial)"@en ;
  schema:description "The Macdonald trial made postoperative chemoradiation the US standard for resected stomach cancer in 2001, though later trials with better surgery and chemotherapy have largely replaced it."@en ;
  schema:url <https://onco.cc/trials/int-0116/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa010187> ;
  onco:status "positive" ;
  onco:tag "radiation-wave4" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/leucovorin/> ;
  onco:companies <https://onco.cc/companies/swog/> ;
  onco:terms <https://onco.cc/terms/chemoradiation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-macdonald-n-engl-j-med/> .