# OnCo record inter-b-nhl-ritux-2010 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/inter-b-nhl-ritux-2010/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "inter-b-nhl-ritux-2010", "NCT01516580" ;
  schema:name "Inter-B-NHL Ritux 2010"@en ;
  schema:description "Adding the antibody rituximab to intensive chemotherapy in children with high-risk Burkitt and related lymphomas cut treatment failures by about two-thirds, making an already curable disease more so. It is the model of a joint European-North American children's cancer trial."@en ;
  schema:url <https://onco.cc/trials/inter-b-nhl-ritux-2010/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01516580>, <https://doi.org/10.1056/NEJMoa1915315> ;
  onco:status "positive" ;
  onco:tag "nci-coverage", "paediatric", "haematologic" ;
  onco:phase "3" ;
  schema:startDate "2011-12" ;
  onco:cancers <https://onco.cc/cancers/burkitt-lymphoma/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:targets <https://onco.cc/targets/cd20/> ;
  onco:drugs <https://onco.cc/drugs/rituximab/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/cytarabine-7-3/>, <https://onco.cc/drugs/etoposide/> ;
  onco:companies <https://onco.cc/companies/childrens-oncology-group/> ;
  onco:institutions <https://onco.cc/institutions/gustave-roussy/>, <https://onco.cc/institutions/siop-europe/> ;
  onco:terms <https://onco.cc/terms/hypogammaglobulinaemia/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-minard-colin-n-engl-j-med/> .