# OnCo record interaact (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/interaact/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "interaact", "NCT02051868" ;
  schema:name "InterAACT"@en ;
  schema:alternateName "InterAAct"@en, "IRCI InterAACT"@en, "EA2133"@en ;
  schema:description "InterAACT was the first randomised trial ever run in advanced anal cancer; the two chemotherapy pairs shrank tumours equally often, but carboplatin with paclitaxel caused far fewer serious side effects and patients on it lived longer, so it became the standard chemotherapy backbone."@en ;
  schema:url <https://onco.cc/trials/interaact/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02051868>, <https://clinicaltrials.gov/study/NCT02560298> ;
  onco:status "positive" ;
  onco:tag "soc-trials" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/metastatic-anal-cancer/>, <https://onco.cc/cancers/anal/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:institutions <https://onco.cc/institutions/royal-marsden/>, <https://onco.cc/institutions/ecog-acrin/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-interaact-carboplatin-paclitaxel-advanced-anal-cancer-rao-jco-2020/> .