# OnCo record interferon-alfa (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/interferon-alfa/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "interferon-alfa" ;
  schema:name "Interferon alfa-2a/2b"@en ;
  schema:description "Interferon alfa was the first biologic cancer drug (1986). It treated hairy cell leukaemia, CML, melanoma, kidney cancer and Kaposi sarcoma, and has been replaced almost everywhere by better-tolerated agents."@en ;
  schema:url <https://onco.cc/drugs/interferon-alfa/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Interferon_type_I> ;
  owl:sameAs <http://www.wikidata.org/entity/Q6046488> ;
  schema:citation <https://en.wikipedia.org/wiki/Interferon_type_I> ;
  onco:status "historic" ;
  onco:tag "gap-fill", "historic" ;
  onco:modality "Recombinant type I interferon (cytokine)" ;
  schema:alternateName "Roferon-A / Intron A / Sylatron" ;
  onco:approval "US 1986: Hairy cell leukaemia", "US 1988: AIDS-related Kaposi sarcoma", "US 1995: Adjuvant high-risk melanoma (high-dose)" ;
  onco:cancers <https://onco.cc/cancers/hairy-cell-leukemia/>, <https://onco.cc/cancers/cml/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/kaposi-sarcoma/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/polycythaemia-vera/>, <https://onco.cc/cancers/erdheim-chester-disease/> ;
  onco:technologies <https://onco.cc/technologies/cytokine-therapy/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/>, <https://onco.cc/companies/merck/> ;
  onco:trials <https://onco.cc/trials/euramos-1/> .