# OnCo record interferon-gamma-signature (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/interferon-gamma-signature/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "interferon-gamma-signature" ;
  schema:name "Interferon-gamma gene signature (T-cell-inflamed signature)"@en ;
  schema:alternateName "IFN-gamma signature"@en, "interferon gamma signature"@en, "IFNG signature"@en, "T-cell-inflamed gene expression profile"@en, "T cell-inflamed GEP"@en, "18-gene GEP"@en, "inflamed signature"@en, "hot tumour signature"@en, "immune gene signature"@en, "GEP score"@en, "Tumor Inflammation Signature"@en ;
  schema:description "An interferon-gamma signature is a readout of a handful of genes that T cells switch on when they are already inside a tumour and fighting; tumours with a high score respond to PD-1 drugs more often across many cancer types, but the score is not yet reliable enough to use outside trials."@en ;
  schema:url <https://onco.cc/terms/interferon-gamma-signature/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  onco:related <https://onco.cc/terms/pd-l1-testing/>, <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/tils/>, <https://onco.cc/terms/gene-expression/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/terms/major-pathological-response/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/advanced-melanoma/>, <https://onco.cc/cancers/stage-iii-melanoma/> .