# OnCo record intravasation-ctc-survival (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/intravasation-ctc-survival/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "intravasation-ctc-survival" ;
  schema:name "Intravasation & circulating tumour cells"@en ;
  schema:description "Getting into the bloodstream kills almost every cell that tries: cells are ripped from their neighbours, battered by flow, and hunted by NK cells. Fewer than one in a thousand survive. The ones that do travel in clusters, wear a cloak of platelets, or ride with neutrophils. Liquid biopsies catch what is left."@en ;
  schema:url <https://onco.cc/pathways/intravasation-ctc-survival/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Circulating_tumor_cell> ;
  schema:citation <https://doi.org/10.1016/j.cell.2014.07.013>, <https://doi.org/10.1038/nature17038> ;
  onco:tag "mechanism", "mechanics-atlas" ;
  onco:technologies <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/continuous-ctdna-monitoring/>, <https://onco.cc/technologies/fragmentomics/>, <https://onco.cc/technologies/aspirin-cancer-prevention/>, <https://onco.cc/technologies/cancer-associated-thrombosis/> ;
  onco:targets <https://onco.cc/targets/vegf/>, <https://onco.cc/targets/csf1r/>, <https://onco.cc/targets/epcam/>, <https://onco.cc/targets/pik3ca/> ;
  onco:drugs <https://onco.cc/drugs/signatera/>, <https://onco.cc/drugs/shield/>, <https://onco.cc/drugs/bevacizumab/> ;
  onco:pathways <https://onco.cc/pathways/metastatic-cascade/>, <https://onco.cc/pathways/angiogenic-switch/>, <https://onco.cc/pathways/nk-cell-recognition/>, <https://onco.cc/pathways/emt/>, <https://onco.cc/pathways/pre-metastatic-niche/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/vaf/>, <https://onco.cc/terms/disseminated-tumor-cells/>, <https://onco.cc/terms/activating-invasion-metastasis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-metastasis-biology/>, <https://onco.cc/bottlenecks/b-dormancy-mrd/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-massague-nature/>, <https://onco.cc/key-papers/paper-aceto-cell/> .