# OnCo record io-before-surgery-hnscc (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/io-before-surgery-hnscc/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "io-before-surgery-hnscc" ;
  schema:name "Immunotherapy before surgery rather than with chemoradiation (HNSCC)"@en ;
  schema:description "In head and neck cancer, immunotherapy works when given before surgery but not when given alongside chemoradiation."@en ;
  schema:url <https://onco.cc/pairings/io-before-surgery-hnscc/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03765918>, <https://clinicaltrials.gov/study/NCT02952586> ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/> ;
  onco:trials <https://onco.cc/trials/keynote-689/>, <https://onco.cc/trials/javelin-hn-100/> ;
  onco:pairs <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/imrt-igrt/> .