# OnCo record io-varices-caution (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/io-varices-caution/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "io-varices-caution" ;
  schema:name "Caution: bevacizumab-based regimens with untreated varices"@en ;
  schema:description "Immunotherapy plus bevacizumab is standard in liver cancer, but the anti-VEGF part can cause fatal bleeding from swollen veins in the oesophagus unless they are checked first."@en ;
  schema:url <https://onco.cc/pairings/io-varices-caution/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03434379>, <https://clinicaltrials.gov/study/NCT03298451> ;
  onco:cancers <https://onco.cc/cancers/hcc/> ;
  onco:drugs <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/durvalumab/> ;
  onco:trials <https://onco.cc/trials/imbrave150/>, <https://onco.cc/trials/himalaya/> ;
  onco:pairs <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/terms/hbv-hcv/> .