# OnCo record ipatasertib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ipatasertib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ipatasertib" ;
  schema:name "Ipatasertib"@en ;
  schema:description "Ipatasertib is an experimental small-molecule drug from Hoffmann-La Roche in phase 3 trials for HR-positive / HER2-negative breast cancer and ovarian cancer, aimed at AKT."@en ;
  schema:url <https://onco.cc/drugs/ipatasertib/> ;
  schema:dateModified "2026-09-11"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?intr=GDC-0068>, <https://doi.org/10.1158/1078-0432.CCR-24-0465> ;
  onco:status "phase-3" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "small molecule" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-metastatic/>, <https://onco.cc/cancers/tnbc-early/> ;
  onco:targets <https://onco.cc/targets/akt/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:trials <https://onco.cc/trials/nct05862285/>, <https://onco.cc/trials/nct04931342/>, <https://onco.cc/trials/ipatunity130/>, <https://onco.cc/trials/barbican/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-kim-lotus-ipatasertib-tnbc-lancet-oncol-2017/> .