# OnCo record irae-thyroid (protocol). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/protocols/irae-thyroid/>
  a schema:MedicalGuideline ;
  onco:kind "protocol" ;
  schema:identifier "irae-thyroid" ;
  schema:name "Thyroid inflammation and underactive thyroid from checkpoint inhibitors"@en ;
  schema:alternateName "checkpoint inhibitor thyroiditis"@en, "ICI thyroiditis"@en, "immune-related hypothyroidism"@en, "immunotherapy thyroid problems"@en, "ir-thyroiditis"@en, "immune-related thyrotoxicosis"@en ;
  schema:description "Immunotherapy often inflames the thyroid gland. It can briefly make the thyroid overactive (racing heart, sweating, shakiness) and then underactive (tiredness, feeling cold), and the underactive phase is often permanent. It is found on routine blood tests, treated with tablets rather than steroids, and immunotherapy usually carries on."@en ;
  schema:url <https://onco.cc/protocols/irae-thyroid/> ;
  schema:dateModified "2026-11-11"^^xsd:date ;
  onco:tag "protocol", "irae", "endocrine" ;
  onco:related <https://onco.cc/protocols/irae-hypophysitis-adrenal/>, <https://onco.cc/protocols/checkpoint-inhibitor-baseline-and-monitoring/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/>, <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/durvalumab/>, <https://onco.cc/drugs/cemiplimab/>, <https://onco.cc/drugs/tremelimumab/>, <https://onco.cc/drugs/avelumab/>, <https://onco.cc/drugs/dostarlimab/> ;
  onco:institutions <https://onco.cc/institutions/sitc/>, <https://onco.cc/institutions/asco/>, <https://onco.cc/institutions/esmo/> ;
  onco:terms <https://onco.cc/terms/immune-endocrinopathy/>, <https://onco.cc/terms/irae/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-asco-irae-guideline-jco-2021/> .