# OnCo record irae (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/irae/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "irae" ;
  schema:name "Immune-related adverse events (irAEs)"@en ;
  schema:alternateName "immune-related adverse event"@en ;
  schema:description "Immune-related adverse events (irAEs) are the autoimmune side effects of checkpoint inhibitors: colitis, thyroid problems, rash, hepatitis, pneumonitis."@en ;
  schema:url <https://onco.cc/terms/irae/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/j.annonc.2022.10.001>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/pembrolizumab>, <https://breastcancernow.org/about-breast-cancer/treatment/targeted-therapy/pembrolizumab-keytruda>, <https://doi.org/10.1200/JCO.21.01440>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/pembrolizumab>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/durvalumab>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/atezolizumab> ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/sclc/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-haanen-ann-oncol/> .