# OnCo record irf4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/irf4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "irf4" ;
  schema:name "IRF4"@en ;
  schema:alternateName "MUM1"@en, "LSIRF"@en, "interferon regulatory factor 4"@en, "IRF4" ;
  schema:description "IRF4 is a master transcription factor of plasma cells and a protein myeloma cells cannot do without. Lenalidomide and its successors lower IRF4 by destroying the two factors, Ikaros and Aiolos, that keep it switched on."@en ;
  schema:url <https://onco.cc/targets/irf4/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6119>, <https://www.uniprot.org/uniprotkb/Q15306/entry>, <https://www.ncbi.nlm.nih.gov/gene/3662> ;
  onco:tag "wave5-target" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6119>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000137265>, <https://www.uniprot.org/uniprotkb/Q15306/entry>, <https://www.ncbi.nlm.nih.gov/gene/3662> ;
  onco:related <https://onco.cc/drugs/lenalidomide/>, <https://onco.cc/drugs/golcadomide/>, <https://onco.cc/targets/ikzf1/>, <https://onco.cc/targets/ikzf3/>, <https://onco.cc/pathways/myc/> ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/celmods/> ;
  onco:pathways <https://onco.cc/pathways/transcription-addiction/>, <https://onco.cc/pathways/myc/> .