# OnCo record irf8 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/irf8/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "irf8" ;
  schema:name "IRF8"@en ;
  schema:alternateName "interferon regulatory factor 8"@en, "Interferon regulatory factor 8"@en, "IRF-8"@en, "ICSBP"@en, "ICSBP1"@en, "IRF8" ;
  schema:description "IRF8 (Interferon regulatory factor 8) is a protein that switches other genes on and off. The public catalogues list it as a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Leukaemia, Non-Hodgkin lymphoma and Diffuse large B-cell lymphoma."@en ;
  schema:url <https://onco.cc/targets/irf8/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5358>, <https://www.uniprot.org/uniprotkb/Q02556/entry>, <https://www.ncbi.nlm.nih.gov/gene/3394>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000140968> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:5358>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000140968>, <https://www.uniprot.org/uniprotkb/Q02556/entry>, <https://www.ncbi.nlm.nih.gov/gene/3394> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/dlbcl/> .