# OnCo record itk (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/itk/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "itk" ;
  schema:name "ITK"@en ;
  schema:alternateName "IL2 inducible T cell kinase"@en, "Tyrosine-protein kinase ITK/TSK"@en, "PSCTK2"@en, "ITK" ;
  schema:description "ITK (Tyrosine-protein kinase ITK/TSK) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, and an approved or late-stage drug is recorded against it. Tied to Renal cell carcinoma and Sarcomas."@en ;
  schema:url <https://onco.cc/targets/itk/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6171>, <https://www.uniprot.org/uniprotkb/Q08881/entry>, <https://www.ncbi.nlm.nih.gov/gene/3702>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000113263> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6171>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000113263>, <https://www.uniprot.org/uniprotkb/Q08881/entry>, <https://www.ncbi.nlm.nih.gov/gene/3702> ;
  onco:related <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:drugs <https://onco.cc/drugs/acalabrutinib/>, <https://onco.cc/drugs/ibrutinib/>, <https://onco.cc/drugs/soquelitinib/> .