# OnCo record ivonescimab (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ivonescimab/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ivonescimab" ;
  schema:name "Ivonescimab"@en ;
  schema:description "A Chinese bispecific that beat Keytruda head-to-head on progression-free survival in lung cancer, the first drug ever to do so."@en ;
  schema:url <https://onco.cc/drugs/ivonescimab/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?intr=AK112> ;
  onco:status "approved" ;
  onco:modality "Bispecific antibody (PD-1×VEGF)" ;
  onco:approval "China 2024: EGFR-mutant NSCLC after TKI (with chemotherapy); first-line PD-L1+ NSCLC" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/pdl1-high-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/vegf/> ;
  onco:companies <https://onco.cc/companies/akeso/>, <https://onco.cc/companies/summit-therapeutics/> ;
  onco:trials <https://onco.cc/trials/nct07010263/>, <https://onco.cc/trials/nct06767527/>, <https://onco.cc/trials/nct06928389/>, <https://onco.cc/trials/nct06396065/>, <https://onco.cc/trials/nct06767514/>, <https://onco.cc/trials/nct05840016/>, <https://onco.cc/trials/nct06686030/>, <https://onco.cc/trials/nct05846867/>, <https://onco.cc/trials/nct06646055/>, <https://onco.cc/trials/nct07397338/>, <https://onco.cc/trials/nct07208773/>, <https://onco.cc/trials/nct05904379/>, <https://onco.cc/trials/nct07052253/>, <https://onco.cc/trials/nct07245446/>, <https://onco.cc/trials/nct06560112/>, <https://onco.cc/trials/nct07623356/>, <https://onco.cc/trials/nct05382442/>, <https://onco.cc/trials/nct05247684/>, <https://onco.cc/trials/nct07669779/>, <https://onco.cc/trials/nct06530251/>, <https://onco.cc/trials/nct07815665/>, <https://onco.cc/trials/nct06953999/>, <https://onco.cc/trials/nct06877650/> .