# OnCo record j-alex (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/j-alex/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "j-alex" ;
  schema:name "J-ALEX"@en ;
  schema:description "The Japanese trial that beat crizotinib with alectinib first, at half the dose used everywhere else, and was stopped early because the difference was so large."@en ;
  schema:url <https://onco.cc/trials/j-alex/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1016/S0140-6736(17)30565-2>, <https://www.clinicaltrials.jp/cti-user/trial/ShowDirect.jsp?japicId=JapicCTI-132316> ;
  onco:status "positive" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/alk-positive-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/alk/> ;
  onco:drugs <https://onco.cc/drugs/alectinib/>, <https://onco.cc/drugs/crizotinib/> ;
  onco:companies <https://onco.cc/companies/chugai/> ;
  onco:terms <https://onco.cc/terms/tki-term/>, <https://onco.cc/terms/brain-metastases/> ;
  onco:trials <https://onco.cc/trials/alex/>, <https://onco.cc/trials/alesia/>, <https://onco.cc/trials/profile-1014/> .