# OnCo record jak2-v617f (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/jak2-v617f/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "jak2-v617f" ;
  schema:name "JAK2 V617F"@en ;
  schema:description "A single letter change in the JAK2 gene that jams the growth signal for blood cells in the on position. Almost everyone with polycythaemia vera has it, as do about half of those with essential thrombocythaemia or myelofibrosis."@en ;
  schema:url <https://onco.cc/terms/jak2-v617f/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Janus_kinase_2> ;
  schema:citation <https://en.wikipedia.org/wiki/Janus_kinase_2> ;
  onco:tag "polycythaemia-vera", "mpn" ;
  onco:cancers <https://onco.cc/cancers/polycythaemia-vera/>, <https://onco.cc/cancers/myeloproliferative-neoplasms/> ;
  onco:targets <https://onco.cc/targets/jak2/> ;
  onco:drugs <https://onco.cc/drugs/ruxolitinib/>, <https://onco.cc/drugs/ropeginterferon-alfa-2b/> .