# OnCo record jak3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/jak3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "jak3" ;
  schema:name "JAK3"@en ;
  schema:alternateName "Janus kinase 3"@en, "Tyrosine-protein kinase JAK3"@en, "L-JAK"@en, "JAK3_HUMAN"@en, "JAK-3"@en, "JAK3" ;
  schema:description "JAK3 (Tyrosine-protein kinase JAK3) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, an oncogene driver and a biomarker, and an approved or late-stage drug is recorded against it. Tied to Myeloproliferative neoplasms, Leukaemia, Non-Hodgkin lymphoma and 5 more."@en ;
  schema:url <https://onco.cc/targets/jak3/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6193>, <https://www.uniprot.org/uniprotkb/P52333/entry>, <https://www.ncbi.nlm.nih.gov/gene/3718>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000105639> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6193>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000105639>, <https://www.uniprot.org/uniprotkb/P52333/entry>, <https://www.ncbi.nlm.nih.gov/gene/3718> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/nsclc/> .