# OnCo record kit (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/kit/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "kit" ;
  schema:name "KIT"@en ;
  schema:description "KIT mutation is the driver behind most gastrointestinal stromal tumours, and the reason imatinib turned a sarcoma with a median survival of about a year into a chronic disease."@en ;
  schema:url <https://onco.cc/targets/kit/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CD117>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6342>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000157404>, <https://www.uniprot.org/uniprotkb/P10721/entry>, <https://www.ncbi.nlm.nih.gov/gene/3815> ;
  schema:citation <https://en.wikipedia.org/wiki/CD117> ;
  onco:tag "driver", "kinase" ;
  schema:alternateName "KIT" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1987"^^xsd:gYear ;
  onco:related <https://onco.cc/biomarkers/kit-d816v/> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/bezuclastinib/>, <https://onco.cc/drugs/al2846/>, <https://onco.cc/drugs/chiauranib/> ;
  onco:companies <https://onco.cc/companies/blueprint-medicines/>, <https://onco.cc/companies/cogent-biosciences/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/aml-signalling/> .