# OnCo record kmt2a (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/kmt2a/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "kmt2a" ;
  schema:name "KMT2A (MLL) rearrangement"@en ;
  schema:alternateName "KMT2A rearrangement"@en, "KMT2A-rearranged"@en, "KMT2A-r"@en, "KMT2Ar"@en, "KMT2A fusion"@en, "MLL-rearranged"@en, "MLL rearrangement"@en, "MLLr"@en, "MLL-r"@en, "11q23 rearrangement"@en, "KMT2A partner gene"@en, "KMT2A" ;
  schema:description "A gene fusion that drives an aggressive leukaemia in infants and adults. It cannot be blocked directly, but the scaffold protein it depends on (menin) can."@en ;
  schema:url <https://onco.cc/targets/kmt2a/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/KMT2A>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7132>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000118058>, <https://www.uniprot.org/uniprotkb/Q03164/entry>, <https://www.ncbi.nlm.nih.gov/gene/4297> ;
  owl:sameAs <http://www.wikidata.org/entity/Q18029164> ;
  schema:citation <https://en.wikipedia.org/wiki/KMT2A> ;
  onco:tag "driver", "fusion" ;
  onco:targetClass "transcription" ;
  onco:firstDescribed "1992"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/menin/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:drugs <https://onco.cc/drugs/revumenib/>, <https://onco.cc/drugs/ziftomenib/> .