# OnCo record kmt2d (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/kmt2d/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "kmt2d" ;
  schema:name "KMT2D"@en ;
  schema:alternateName "lysine methyltransferase 2D"@en, "Histone-lysine N-methyltransferase 2D"@en, "MLL4"@en, "CAGL114"@en, "TNRC21"@en, "MLL2"@en, "KMT2D" ;
  schema:description "KMT2D (Histone-lysine N-methyltransferase 2D) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Lung cancer, Non-Hodgkin lymphoma, Bladder & urothelial cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/kmt2d/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7133>, <https://www.uniprot.org/uniprotkb/O14686/entry>, <https://www.ncbi.nlm.nih.gov/gene/8085>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000167548> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7133>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000167548>, <https://www.uniprot.org/uniprotkb/O14686/entry>, <https://www.ncbi.nlm.nih.gov/gene/8085> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/neuroendocrine/>, <https://onco.cc/cancers/gastric/> .
